diff --git a/jOOQ/src/main/java/org/jooq/impl/R2DBC.java b/jOOQ/src/main/java/org/jooq/impl/R2DBC.java
index 6e78d39507..a046d608dc 100644
--- a/jOOQ/src/main/java/org/jooq/impl/R2DBC.java
+++ b/jOOQ/src/main/java/org/jooq/impl/R2DBC.java
@@ -37,6 +37,7 @@
  */
 package org.jooq.impl;
 
+import static org.jooq.SQLDialect.MARIADB;
 // ...
 import static org.jooq.ContextConverter.scoped;
 import static org.jooq.conf.ParamType.NAMED;
@@ -68,6 +69,8 @@ import java.time.LocalDateTime;
 import java.time.LocalTime;
 import java.time.Year;
 import java.util.Properties;
+import java.util.Set;
+import java.util.UUID;
 import java.util.concurrent.Callable;
 import java.util.concurrent.ConcurrentHashMap;
 import java.util.concurrent.ConcurrentMap;
@@ -956,6 +959,8 @@ final class R2DBC {
             }
         }
 
+        private static final Set<SQLDialect> NO_SUPPORT_UUID = SQLDialect.supportedBy(MARIADB);
+
         private final Class<?> nullType(Class<?> type) {
 
             // [#11700] Intercept JDBC temporal types, which aren't supported by R2DBC
@@ -973,6 +978,8 @@ final class R2DBC {
                 return String.class;
             else if (type == JSONB.class)
                 return String.class;
+            else if (type == UUID.class && NO_SUPPORT_UUID.contains(c.dialect()))
+                return String.class;
             else if (Enum.class.isAssignableFrom(type))
                 return String.class;
             else if (Interval.class.isAssignableFrom(type))